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Changes to HEPASY and PTTIM Testing
Special Communication:
Immediate Test Changes
Updates to testing are effective as of February 22, 2018. Changes have been bolded in the sections below.
Heparin Anti Xa Assay (HEPASY)
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Specimen Requirement1 mL platelet-poor plasma (Minimum: 0.5 mL) from a 3.2 % sodium citrate (light blue) tube
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StabilityAmbient: Centrifuge within one hour of phlebotomy and test or freeze platelet-poor plasma within 4 hours
Refrigerated: Unacceptable
Frozen: 2 weeks at ≤ minus 20 °C; 6 months at ≤ minus 70 °C
Refrigerated: Unacceptable
Frozen: 2 weeks at ≤ minus 20 °C; 6 months at ≤ minus 70 °C
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Reference Range0–99 Years: Therapeutic range: 0.3 – 0.7 (standard nomogram) IU/mL
0–99 Years: < 0.10 IU/mL
0–99 Years: Stroke or low dose protocol: 0.2 – 0.5 IU/mL
0–99 Years: < 0.10 IU/mL
0–99 Years: Stroke or low dose protocol: 0.2 – 0.5 IU/mL
PTT Incubated Mixing Study (PTTIM): Reference Range
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PT Screen0–1 Days: 7.9–14.8 sec
2–5 Days: 7.4–14.2 sec
6–30 Days: 7.2–13.3 sec
1–3 Months: 7.2–13.2 sec
4–11 Months: 8.3–12.9 sec
1–99 Years: 8.4–13.0 sec
2–5 Days: 7.4–14.2 sec
6–30 Days: 7.2–13.3 sec
1–3 Months: 7.2–13.2 sec
4–11 Months: 8.3–12.9 sec
1–99 Years: 8.4–13.0 sec
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APPT Screen0–1 Days: 28.7–45.1 sec
2–5 Days: 23.3–49.4 sec
6–30 Days: 23.5–45.6 sec
1–3 Months: 22.1–41.4 sec
4–11 Months: 25.8–35.5 sec
1–99 Years: 24.4–33.4 sec
2–5 Days: 23.3–49.4 sec
6–30 Days: 23.5–45.6 sec
1–3 Months: 22.1–41.4 sec
4–11 Months: 25.8–35.5 sec
1–99 Years: 24.4–33.4 sec
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Immediate PTT 1:1 Mix0–99 Years: < 30.9 sec
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Incubated PTT 1:1 Mix0–99 Years: < 33.6 sec
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Thrombin Time0–1 Days: < 17.4 sec
2–5 Days: < 17.9 sec
6–30 Days: < 17.9 sec
1–3 Months: < 18.2 sec
4–11 Months: < 19.1 sec
1–99 Years: < 18.6 sec
2–5 Days: < 17.9 sec
6–30 Days: < 17.9 sec
1–3 Months: < 18.2 sec
4–11 Months: < 19.1 sec
1–99 Years: < 18.6 sec
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Heparin Anti Xa0–99 Years: Therapeutic range: 0.3–0.7 (standard nomogram) IU/mL
0–99 Years: < 0.10 IU/mL
0–99 Years: Stroke or low dose protocol: 0.2 – 0.5 IU/mL
0–99 Years: < 0.10 IU/mL
0–99 Years: Stroke or low dose protocol: 0.2 – 0.5 IU/mL
If you have any questions about these changes, please contact Client Services for assistance.
