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Changes To COMPC1, COMP3A, & COMP4A Testing
Complement C 1 (COMPC1)
Separate specimens must be submitted when multiple tests are ordered.
Specimen Requirements
• 1 mL serum into a Red BD Hemogard™ Serum Tube (No Additive) Tube
• Minimum volume: 0.25 mL
Allow blood to clot for 20 – 60 minutes at room temperature (or 37 °C), then centrifuge. Aliquot serum into a standard aliquot tube, then freeze the specimen immediately on dry ice or at -70 °C.
Do not draw gel separator tubes.
Transporting Specimens
• Transport Temperature: Critical Frozen
Send the frozen specimen via Priority Overnight in a well-insulated container on dry ice.
Thawed specimens or specimens stored at or above -20°C will not be accepted.
Reference Range
• 116,373 – 264,072 units/mL
Complement Component Level 3A (COMP3A)
Separate specimens must be submitted when multiple tests are ordered.
Specimen Requirements
• 1 mL plasma into a Lavender BD Hemogard™ K2EDTA Tube
• Minimum volume: 0.5 mL
Mix well. Centrifuge the specimen at room temperature within 30 minutes of collection, then transfer the plasma to a standard aliquot tube. Immediately freeze the specimen on dry ice or at -70°C.
Transporting Specimens
• Transport Temperature: Critical Frozen
Send the frozen specimen via Priority Overnight in a well-insulated container on dry ice.
Thawed specimens or specimens stored at or above -20°C will not be accepted.
Reference Range
• 0 – 780 ng/mL
Complement Component Level 4A (COMP4A)
Separate specimens must be submitted when multiple tests are ordered.
Specimen Requirements
• 1 mL plasma into a Lavender BD Hemogard™ K2EDTA Tube
• Minimum volume: 0.5 mL
Mix well. Centrifuge at room temperature within 30 minutes of collection, then transfer plasma to a standard aliquot tube and freeze immediately. Plasma may be frozen at -20°C then transferred to dry ice for shipment within 6 hours or immediately frozen on dry ice/at -70°C or below.
Transporting Specimens
• Transport Temperature: Critical Frozen
Send the frozen specimen via Priority Overnight in a well-insulated container on dry ice.
Thawed specimens or specimens stored at room temperature prior to shipment are unacceptable.
Reference Range
• 0 – 2,830 ng/mL
Any additional information regarding this testing will be included in a future Technical Update.
If you have any questions about this change, please contact Client Services for assistance.
