Changes to Melatonin (MELAT) Testing
– 3 mL plasma in a Lavender BD Hemogard™ K2EDTA Tube
Note: Draw two tubes to ensure adequate volume.
– Minimum volume: 1 mL
Patient Preparation: Fasting specimen preferred.
Centrifuge the tubes, then transfer plasma into a standard aliquot tube before freezing the specimen.
Melatonin concentration varies with light and dark cycles: concentration is lower during the day and higher at night.
Patients treated with pituitary or steroid hormones influence the concentration. Hormones should be discontinued for two days prior to collection.
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