Molecular Pathology has been in practice at Cleveland Clinic since 1979, ranking it among the longest histories of any clinical laboratory in the world.
Organized within the Department of Laboratory Medicine of the Robert J. Tomsich Pathology & Laboratory Medicine Institute, the Molecular Pathology Section is composed of two areas: Molecular Diagnostics and Cytogenomics.
Molecular Diagnostics is applied in many areas of medicine including, but not limited to infectious disease, carrier screening, genetic disease, and oncology—including hematopoietic malignancies and solid tumor testing.
Among the technologies used in the Molecular Pathology Section are Next-Generation Sequencing (NGS), real-time polymerase chain reaction (RT-PCR), single base extension detection by mass spectrometry, and many others.
The Cytogenomics Laboratory performs clinical testing for pre- and post-natal constitutional specimens and oncology samples using chromosomal microarrays (CMA), fluorescence in situ hybridization (FISH), and conventional cytogenetics (G-banding).
Our laboratories support our staff pathologists and collaborate with physicians in Cleveland Clinic’s Taussig Cancer Center, Genomic Medicine Institute, Neurological Institute, as well as other relevant departments within our health system.
Laboratory Genetic Counseling
Laboratory genetic counselors support the genetic testing process as liaisons between clinicians and molecular & cytogenetic laboratories.
Our dedicated team of laboratory genetic counselors works closely with the Clinical Genetics Team in the Genomic Medicine Institute to improve the access and delivery of genetic services, and also plays an integral role within the Laboratory Stewardship Committee.