The Breast Pathology Consultative Service offers a range of comprehensive services for the diagnosis and management of nonneoplastic breast conditions and breast carcinoma.
Our subspecialized breast pathology service regularly handles large volumes of neoplastic and nonneoplastic breast diseases.
To complement the traditional histologic diagnosis of breast cancer, our pathologists also provide interpretation of special studies.
Breast Pathology Consultation Services
Primary Diagnosis | Second Opinion Consultation
Histology – Immunohistochemistry – Molecular Analysis
In addition to providing diagnoses, Cleveland Clinic Laboratories offers ancillary testing that helps to guide treatment and therapy decision-making. Test offerings include immunohistochemistry for estrogen receptor (ER), progesterone receptor (PgR), HER2 (ERBB2), androgen receptor (AR), PD-L1 (SP142) for triple-negative breast carcinoma, and mismatch repair protein (MMR) to assess microsatellite stability.
Cleveland Clinic Laboratories features a dedicated FISH lab for HER2 (ERBB2) determination and a molecular oncology laboratory that offers assays for NTRK rearrangements—the results of which may be used to inform larotrectinib therapy—in addition to a 170 Next-Generation Sequencing (NGS) panel that includes analysis for PIK3CA—which may be used to inform alpelisib treatment.
Turnaround for most pathology cases is within 48 hours.
Our staff is available for consultation during any stage of diagnosis or treatment.
Flexible Billing Options
Options include third-party and client billing that can be customized to your needs.
Concise, in-depth reports are available for each consultation.
Breast Pathology Staff
Our breast pathologists are key participants in multidisciplinary breast tumor conferences and closely work alongside breast surgeons, radiation oncologists, radiologists, and oncologists.
Staff is actively engaged in research, collaborating with clinician-scientists and providing pathologic support for clinical trials.
In addition, members of our staff frequently serve as speakers at continuing medical education courses throughout the nation and participate in leading professional organizations to promote our cornerstones of education and excellence in clinical care for all patients.