BK Virus DNA Quantification
Test Mnemonic
BKQUAN
CPT Codes
- 87799 - QTY (1)
LOINC ®
41479-7
Aliases
- BK Polyomavirus
- BK Quant.
- BK Virus PCR
- BKPCR
- BKV
Includes
- Detection and Quantitation of BK Virus by Real-Time PCR
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Plasma | EDTA PPT (White) | Refrigerated | Plasma must be separated within 24 hours of collection If aliquoting is necessary, sterile aliquot tubes must be used. Sample cannot be shared with a test performed outside of Molecular Microbiology. Sample can only be shared with CMVQNT, HCQPCR, HIVRNA, HBVDNU, EBVQNT, or BKQUAN. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | EDTA (Lavender) | Refrigerated | Plasma must be separated within 24 hours of collection If aliquoting is necessary, sterile aliquot tubes must be used. Sample cannot be shared with a test performed outside of Molecular Microbiology. Sample can only be shared with CMVQNT, HCQPCR, HIVRNA, HBVDNU, EBVQNT, or BKQUAN. | ||
| 2 mL | Plasma | EDTA PPT (White) | Frozen | Plasma must be separated within 24 hours of collection. Prior to freezing, specimen must be aliquoted into a sterile secondary tube. Sample cannot be shared with a test performed outside of Molecular Microbiology. Sample can only be shared with CMVQNT, HCQPCR, HIVRNA, HBVDNU, EBVQNT, or BKQUAN. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Sample cannot be shared with a test performed outside of Molecular Microbiology. Sample can only be shared with CMVQNT, HCQPCR, HIVRNA, HBVDNU, EBVQNT, or BKQUAN. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 24 hours |
| Refrigerated | 6 days |
| Frozen | 6 months |
Days Performed
5 days per week
Turnaround Time
5 days
Methodology
| Name | Description |
|---|---|
| Polymerase Chain Reaction (PCR) |
Reference Range
| BK DNA (IU/mL) | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| ~ | IU/mL | ||||
| BK DNA (Log IU/mL) | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| ~ | log IU/mL | ||||
| BKV DNA Quant | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | BKV DNA not detected by PCR. | IU/mL |
Special Info
Plasma must be separated within 24 hours of collection. A sterile aliquot tubes must be used.
Clinical Info
The detection and monitoring of BK viral loads is indicated in renal transplant recipients at risk for BK allograft nephropathy, and occasionally in other immunocompromised patients. BK virus is associated with renal allograft nephropathy, hemorrhagic cystitis, ureteral stenosis and other urinary tract diseases. This test is used to monitor the amount of virus present in the plasma of the patient.