Chromosome Analysis, Amniotic Fluid
Test Mnemonic
FAMCYT
CPT Codes
- 88235 - QTY (1)
- 88269 - QTY (1)
- 88280 - QTY (1)
- 88285 - QTY (1)
Includes
- Specimen Type
- Cells Counted
- Colonies
- Cells Analyzed
- Cells Karyotyped
- GTG Band Resolution Achieved
- Cytogenetic Diagnosis
- Cytogenetic Interpretation
- Director Review:
Performing Laboratory
Integrated Genetics/Labcorp
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 30 mL | Fluid, amniotic | Clean container | Ambient | Discard first 2 mL of amniotic fluid. Collect specimen in two screw top plastic tubes. Do not centrifuge. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 20 mL | Fluid, amniotic | Clean container | Ambient | Early amniocentesis. Discard first 2 mL of amniotic fluid. Collect specimen in two screw top plastic tubes. Do not centrifuge. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 4 days |
| Refrigerated | 4 days |
| Frozen | Unacceptable |
Days Performed
Mon - Fri
Turnaround Time
10 - 14 days
Methodology
| Name | Description |
|---|---|
| Culture | |
| Chromosome Analysis |
Reference Range
Special Info
Discard first 2 mL of amniotic fluid. Collect specimen in two screw top plastic tubes. Do not centrifuge. Specimens found not to be amniotic fluid, grossly contaminated with blood cells, frozen or in a container with a rubber stopper (rubber is toxic to amniocytes) will be rejected.
Clinical Info
The test determines fetal karyotype and allows prenatal detection of chromosomal rearrangements, aneuploidy, or mosaicism.