Coccidioides IgG and IgM Antibodies
Test Mnemonic
COCIMG
CPT Codes
- 86635 - QTY (2)
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Serum | SST (Gold) | Refrigerated | Separate serum from cells ASAP or within 2 hours of collection and transfer serum to standard aliquot tube. Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent." |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.6 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 48 hours |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 1 year (Avoid repeated freeze/thaw cycles) |
Days Performed
Sun - Sat
Turnaround Time
2 - 4 days
Methodology
| Name | Description |
|---|---|
| Enzyme-Linked Immunosorbent Assay (ELISA) |
Reference Range
| Coccidioides IgG Antibody | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Freetext | Negative: 0.9 IV or less; No significant level of Coccidioides IgG antibody detected. | Freetext | Equivocal: 1.0 - 1.4 IV; Questionable presence of Coccidioides IgG antibody detected. Repeat testing in 10-14 days may be helpful. | Freetext | Positive: 1.5 IV or greater; Presence of IgG antibody to Coccidioides detected, suggestive of current or past infection. |
| Coccidioides IgM Antibody | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Freetext | Negative: 0.9 IV or less; No significant level of Coccidioides IgM antibody detected. | Freetext | Equivocal: 1.0 - 1.4 IV; Questionable presence of Coccidioides IgM antibody detected. Repeat testing in 10-14 days may be helpful. | Freetext | Positive: 1.5 IV or greater; Presence of IgM antibody to Coccidioides detected, suggestive of current or recent infection. |
Special Info
Non-serum specimens and serum that is contaminated, hemolyzed, icteric or lipemic will be rejected. This test is New York DOH approved.
Clinical Info
May aid in the diagnosis of coccidioidomycosis (Valley fever). Negative fungal serology does not rule out the possibility of current infection. Note: This immunoassay uses recombinant and native Coccidioides antigens, including CF and TP antigens.