Cryptococcus Ag Detection
- 87899 - QTY (1)
- Antigen Detection, Cryptococcus
Cleveland Clinic Laboratories
|Cerebrospinal fluid (CSF)
|Transport recommendations: Refrigerated: 72 hrs, Frozen; indefinitely.
|1 - 2 mL
|Serum should be separated from cells ASAP after collection by centrifuging. Transport recommendations: Refrigerated: 72 hrs, Frozen; indefinitely.
Minimum Specimen Requirements
|for CSF specimens
|Serum separated from clot: 1 week; Serum not separated from clot: 72 hours; CSF: 72 hours
|Serum: Indefinitely; CSF: Indefinitely
Sun - Sat
|Line Immunoassay (INNO-LIA)
|Cryptococcal Ag Result
Testing can be performed only on CSF or serum. Test cannot be performed if specimen is hemolyzed or grossly contaminated. If Cryptococcal Antigen Detection is positive, a titer will be performed at an additional charge with CPT code 87899 applied. If Cryptococcal Antigen Detection is positive, culture will be reflexed.
The Cryptococcal Antigen test is used to determine the presence of Cryptococcus neoformans antigen in CSF or serum using lateral flow methodology. Cryptococcal disease is known to occur more frequently in immunosuppressed patients and may follow exposure to bird droppings. False positives may occur in patients with T. beigelii infections or high levels of Human anti-mouse antibodies (HAMA). Positive specimens are titered.