Maternal Cell Contamination
Test Mnemonic
MATRNL
CPT Codes
- 81265 - QTY (1)
Aliases
- Maternal Cell Contamination Analysis
Includes
- Specimen Type
- Result
- Maternal Cell Contamination
- Director Review
Performing Laboratory
Integrated Genetics/Labcorp
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 7 mL | Whole blood | ACD A (Yellow) | Ambient |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 7 mL | Whole blood | EDTA (Lavender) | Ambient |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 3 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 21 days |
| Refrigerated | 21 days |
| Frozen | Unacceptable |
Days Performed
Mon - Sat
Turnaround Time
13 - 22 days
Methodology
| Name | Description |
|---|---|
| Capillary Electrophoresis (CE) | |
| Polymerase Chain Reaction (PCR) |
Reference Range
Special Info
This test is only available in combination with LabCorp Integrated Genetics prenatal genetic testing. A maternal sample is required for maternal cell contamination testing in conjunction with all Integrated Genetics prenatal molecular testing. Causes for rejection: Frozen specimen, hemolysis, quantity not sufficient for analysis, improper container, unlabeled or mislabeled specimen.
Clinical Info
Both amniotic fluid and CVS may have maternal cells present in the sample. These do not usually interfere with the accuracy of chromosome analysis, but are well-recognized as a potential source of error in molecular diagnosis.
Clinical Limitation
False positive or false negative results may occur for reasons that include genetic variants, technical handling, blood transfusions, bone marrow transplantation, mislabeling of samples, or erroneous representation of family relationships.