Neisseria meningitidis IgG Vaccine Response
Test Mnemonic
NMEN
CPT Codes
- 86317 - QTY (4)
Aliases
- Neisseria meningitidis Tetravalent Antibodies
Includes
- Serogroup A
- Serogroup C
- Serogroup Y
- Serogroup W-135
Performing Laboratory
Focus Laboratories MRL
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | Serum | SST (Gold) | Refrigerated |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | Serum | No additive (Red) | Refrigerated |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.3 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 5 days |
| Refrigerated | 2 weeks |
| Frozen | 1 month |
Days Performed
Tue
Turnaround Time
2 - 8 days
Methodology
| Name | Description |
|---|---|
| Multi Analyte Immunodetection (MAID) |
Reference Range
| Serogroup A | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | < 4.0 | ug/mL | |||
| Serogroup C | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | < 5.0 | ug/mL | |||
| Serogroup W-135 | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | <3.0 | ug/mL | |||
| Serogroup Y | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | < 4.0 | ug/mL |
Special Info
Plasma is unacceptable.
Clinical Info
This assay measures serum IgG antibodies recognizing polysaccharide antigens from the four N. meninigitidis serogroups included in the licensed meningococcal vaccine. The meningococcal vaccine response is best evaluated by testing pre-vaccination and post-vaccination samples in parallel. A two-fold or greater increase for at least two serogroups is expected when comparing post-vaccination to pre-vaccination results. N. meningitidis IgG levels peak approximately one month post vaccination, but decline markedly by two years.