Prothrombin Time and PTT Elevation Diagnostic Panel

Prothrombin Time and PTT Elevation Diagnostic Panel Print

Test Mnemonic

PTPTTE

CPT Codes

85390 - QTY (1)
85520 - QTY (1)
85610 - QTY (1)
85611 - QTY (1)
85670 - QTY (1)
85730 - QTY (1)
85732 - QTY (2)

Aliases

Elevated PT / PTT Panel

Performing Laboratory

Cleveland Clinic Laboratories

Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
4.5 mL	Plasma	Sodium citrate (Lt. Blue)		Frozen

Stability

Environmental Condition	Description
Ambient	4 hours
Frozen	14 days at -20 C; 6 months at -70 C
Refrigerated	Unacceptable

Days Performed

Mon - Fri

Turnaround Time

1 - 3 days

Methodology

Name	Description
Refer to individual components

Reference Range

APTT Screen
Sex	Age From	Age To	Type	Range	Range Unit
	Days	1 Days	Normal	28.2-47.4	sec
	1 Months	3 Months	Normal	21.7-43.5	sec
	2 Days	5 Days	Normal	22.9-52.0	sec
	6 Days	30 Days	Normal	23.1-48.0	sec
	4 Months	11 Months	Normal	25.3-37.3	sec
	1 Years	5 Years	Normal	21.3-31.6	sec
	6 Years	10 Years	Normal	23.1-31.6	sec
	11 Years	16 Years	Normal	23.1-32.5	sec
	17 Years	99 Years	Normal	24.0-35.1	sec
Immediate PTT 1:1 Mix
Sex	Age From	Age To	Type	Range	Range Unit
	Years	99 Years	Normal	< 33.2	sec
Incubated PTT 1:1 Mix
Sex	Age From	Age To	Type	Range	Range Unit
	Years	99 Years	Normal	<35.0	sec
PT 1:1 Mix
Sex	Age From	Age To	Type	Range	Range Unit
	Days	1 Days	Normal	<14.9	sec
	2 Days	5 Days	Normal	<14.3	sec
	6 Days	30 Days	Normal	<13.4	sec
	1 Months	3 Months	Normal	<13.3	sec
	4 Months	11 Months	Normal	<13.0	sec
	1 Years	5 Years	Normal	<10.7	sec
	6 Years	10 Years	Normal	<11.3	sec
	11 Years	16 Years	Normal	<11.2	sec
	17 Years	99 Years	Normal	<13.1	sec

Special Info

Indicate clearly if patient is on heparin, coumadin, direct thrombin inhibitor or thrombolytic therapy. Submit 'Coagulation Consultation Patient History Form.' If tests are abnormal, the following tests may be added and billed: Fibrinogen (CPT 85384), Fibrinogen Ag (CPT 85385), D-Dimer (CPT 85379), Reptilase (CPT 85635).

Clinical Info

Note: It is recommended that the abnormal PT and APTT be confirmed before ordering this panel. This panel is recommended for the evaluation of coagulation disorders in patients with both a prolonged PT and a prolonged APTT, whether or not there is a bleeding diathesis. Disorders that may be investigated include common pathway coagulation factor deficiencies (fibrinogen, factors II, V, X), coagulation factor inhibitors, non-specific inhibitors, vitamin K deficiency, hepatic coagulopathy, disseminated intravascular coagulation (DIC), lupus anticoagulants, hypofibrinogenemia, dysfibrinogenemia, or anticoagulant drug effects.