Prothrombin Time and PTT Elevation Diagnostic Panel

Test Mnemonic


CPT Codes

  • 85390 - QTY (1)
  • 85520 - QTY (1)
  • 85610 - QTY (1)
  • 85611 - QTY (1)
  • 85670 - QTY (1)
  • 85730 - QTY (1)
  • 85732 - QTY (2)


  • Elevated PT / PTT Panel

Performing Laboratory

Cleveland Clinic Laboratories

Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
4.5 mLPlasmaSodium citrate (Lt. Blue) Frozen 


Environmental Condition Description
Ambient4 hours
Frozen14 days at -20 C; 6 months at -70 C

Days Performed

Mon - Fri

Turnaround Time

1 - 3 days


Name Description
Refer to individual components 

Reference Range

APTT Screen
Sex Age From Age To Type Range Range Unit
   Days1 DaysNormal28.2-47.4sec
 1 Months3 MonthsNormal21.7-43.5sec
 2 Days5 DaysNormal22.9-52.0sec
 6 Days30 DaysNormal23.1-48.0sec
 4 Months11 MonthsNormal25.3-37.3sec
 1 Years5 YearsNormal21.3-31.6sec
 6 Years10 YearsNormal23.1-31.6sec
 11 Years16 YearsNormal23.1-32.5sec
 17 Years99 YearsNormal24.0-35.1sec
Immediate PTT 1:1 Mix
Sex Age From Age To Type Range Range Unit
   Years99 YearsNormal< 33.2sec
Incubated PTT 1:1 Mix
Sex Age From Age To Type Range Range Unit
   Years99 YearsNormal<35.0sec
PT 1:1 Mix
Sex Age From Age To Type Range Range Unit
   Days1 DaysNormal<14.9sec
 2 Days5 DaysNormal<14.3sec
 6 Days30 DaysNormal<13.4sec
 1 Months3 MonthsNormal<13.3sec
 4 Months11 MonthsNormal<13.0sec
 1 Years5 YearsNormal<10.7sec
 6 Years10 YearsNormal<11.3sec
 11 Years16 YearsNormal<11.2sec
 17 Years99 YearsNormal<13.1sec

Special Info

Indicate clearly if patient is on heparin, coumadin, direct thrombin inhibitor or thrombolytic therapy. Submit 'Coagulation Consultation Patient History Form.' If tests are abnormal, the following tests may be added and billed: Fibrinogen (CPT 85384), Fibrinogen Ag (CPT 85385), D-Dimer (CPT 85379), Reptilase (CPT 85635).

Clinical Info

Note: It is recommended that the abnormal PT and APTT be confirmed before ordering this panel. This panel is recommended for the evaluation of coagulation disorders in patients with both a prolonged PT and a prolonged APTT, whether or not there is a bleeding diathesis. Disorders that may be investigated include common pathway coagulation factor deficiencies (fibrinogen, factors II, V, X), coagulation factor inhibitors, non-specific inhibitors, vitamin K deficiency, hepatic coagulopathy, disseminated intravascular coagulation (DIC), lupus anticoagulants, hypofibrinogenemia, dysfibrinogenemia, or anticoagulant drug effects.