Chromosomal Microarray SNP, Constitutional
Test Mnemonic
CRMSNP
CPT Codes
- 81229 - QTY (1)
Aliases
- CGH, CMA, SNP, Array
Includes
- plus oligonucleotide probes
- platform includes single nucleotide polymorphism (SNP) probes
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 4 mL | Whole blood | EDTA (Lavender) | Ambient | If aliquoting is necessary, sterile aliquot tubes must be used. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Minimum of 1mL of Whole blood, EDTA (Lavender). If aliquoting is necessary, sterile aliquot tubes must be used. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | The following specimens are considered unacceptable: 1. Clotted, frozen or hemolyed peripheral blood, 2. Samples collected in the incorrect anticoagulant, and 3. Improperly labeled specimen. |
Days Performed
3 days per week
Turnaround Time
14 days
Methodology
| Name | Description |
|---|---|
| Comparative genomic hybridization(CGH) |
Reference Range
Special Info
Recommended Use: Inherited or congenital anomalies or disorders. Provide clinical indication for analysis with the specimen. Clinical Indications: Individuals with unexplained intellectual disability, developmental delay, autism, dysmorphic features, or other phenotypic anomalies. Individuals with a suspicion of a chromosomal abnormality or microduplication/deletion syndrome with a normal karyotype. Determining the size of a duplication/deletion involved in an unbalanced translocation. Assessing possible cryptic duplications/deletions in an individual with an apparently balanced karyotype, but with phenotypic abnormalities. Triploidy, uniparental disomy (UPD) , absence of heteorzygosity to determine the degree of relatedness by identity-by-descent (autozygosity).
Clinical Info
Reflexed tests: Chromosomes and FISH. This test may incur an additional charge.
Clinical Reference
Lab and extension: Cytogenetics Lab/ 216-444-2489