Factor II Assay




Test Mnemonic

FIIC

CPT Codes

  • 85210 - QTY (1)

LOINC ®

3289-6

Aliases

  • Prothrombin Assay

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
Volume2 mLTypePlasmaContainerSodium citrate (Lt. Blue)Collect Temperature Transport TemperatureFrozenSpecial InstructionsIndicate previous prothrombin and partial thromboplastin time results on requisition.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
Volume1 mLType Container Collect Temperature Transport Temperature Special Instructions 

Stability

Environmental Condition Description
Environmental ConditionAmbientDescription4 hours
Environmental ConditionRefrigeratedDescriptionUnacceptable
Environmental ConditionFrozenDescription14 days at -20 C; 6 months at -70 C

Days Performed

Mon - Fri

Turnaround Time

1 - 3 days

Methodology

Name Description
NameClotting AssayDescription 

Reference Range

Factor II Assay
Sex Age From Age To Type Range Range Unit
Factor II Assay Sex  DaysAge From1 DaysAge ToNormalType29 - 72Range%
Factor II Assay Sex2 DaysAge From5 DaysAge ToNormalType36 - 96Range%
Factor II Assay Sex6 DaysAge From30 DaysAge ToNormalType37 - 106Range%
Factor II Assay Sex1 MonthsAge From3 MonthsAge ToNormalType50 - 109Range%
Factor II Assay Sex4 MonthsAge From11 MonthsAge ToNormalType66 - 120Range%
Factor II Assay Sex1 YearsAge From5 YearsAge ToNormalType78 - 120Range%
Factor II Assay Sex6 YearsAge From10 YearsAge ToNormalType74-111Range%
Factor II Assay Sex11 YearsAge From16 YearsAge ToNormalType67-108Range%
Factor II Assay Sex17 YearsAge From99 YearsAge ToNormalType77-151Range%
Factor II Assay Sex  YearsAge From99 YearsAge ToUrgentTypeAfter Pathologist Review: < 5Range%

Special Info

This test does not detect the prothrombin G20210A polymorphism. For that assay order Prothrombin Gene Mutation. 3.2% sodium citrate is the preferred anticoagulant recommended by CLSI.

Clinical Info

Detecting coagulation deficiency of factor II. Factor II deficiency may be seen in congenital Factor II deficiency, in liver disease, vitamin K deficiency, coumadin therapy or DIC. Some patients with lupus anticoagulants may also have hypoprothrombinemia.