Macroprolactin | Cleveland Clinic Laboratories

Macroprolactin Print

Test Mnemonic

MACPRO

CPT Codes

84146 - QTY (2)

Aliases

Macroprolactin by PEG
Macroprolactin by PEG

Performing Laboratory

ARUP

Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
1 mL	Serum	SST (Gold)		Frozen	Allow specimen to clot completely at room temperature. Separate serum from cells and transfer into standard aliquot tube.

Alternate Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
1 mL	Plasma	Lithium heparin PST (Lt. Green)		Frozen	Separate plasma from cells and transfer into standard aliquot tube.
1 mL	Plasma	EDTA (Lavender)		Frozen	Separate plasma from cells and transfer into standard aliquot tube.

Minimum Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
0.5 mL

Stability

Environmental Condition	Description
Frozen	After separation from cells: 1 month
Refrigerated	After separation from cells: 7 days
Ambient	After separation from cells: 8 hours

Days Performed

Sun

Turnaround Time

2 - 9 days

Methodology

Name	Description
Chemiluminescence Immunoassay (CLIA)

Reference Range

Monomeric Prolactin
Sex	Age From	Age To	Type	Range	Range Unit
Male	1 Years	9 Years	Normal	2.1 - 13.3	ng/mL
Male	10 Years	99 Years	Normal	2.1 - 13.3	ng/mL
Female	1 Years	9 Years	Normal	2.1 - 13.3	ng/mL
Female	10 Years	99 Years	Normal	2.8 - 19.5	ng/mL
Monomeric Prolactin Percent
Sex	Age From	Age To	Type	Range	Range Unit
				Greater than 50%
Prolactin
Sex	Age From	Age To	Type	Range	Range Unit
Male	1 Years	9 Years	Normal	2.1 - 17.7	ng/mL
Male	10 Years	99 Years	Normal	2.1 - 17.7	ng/mL
Female	1 Years	9 Years	Normal	2.1 - 17.7	ng/mL
Female	10 Years	99 Years	Normal	2.8 - 29.2	ng/mL

Special Info

Allow serum specimen to clot completely at room temperature.

Clinical Info

If the % Monomeric Prolactin is 40-50%, then the result is indeterminate for macroprolactin. If the % Monomeric Prolactin is less than 40%, then this indicates the presence of macroprolactin. A Monomeric Prolactin result above the upper reference limit is consistent with hyperprolactinemia. Monomeric Prolactin was determined by PEG precipitation. Macroprolactin is precipitated by PEG and is not measured.