Maternal Serum Screen, Alpha Fetoprotein
Test Mnemonic
AFPMAT
CPT Codes
- 82105 - QTY (1)
Aliases
- AFP Neural Tube Defects
Includes
- Patient's AFP
- MoM for AFP
- Maternal Screen Interpretation
- Maternal Age At Delivery
- Maternal Weight
- Estimated Due Date
- Gestational Age Calculated at Collection
- Dating
- Number of Fetuses
- Maternal Race
- Insulin Req Maternal Diabetes
- Smoking
- Family Hx Neural Tube Defect
- Specimen
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated | Specimen must be drawn between 14 weeks, 0 days and 24 weeks, 6 days gestation. Separate from cells ASAP or within 2 hours of collection and transfer to standard aliquot tube. See Special Information for list of required patient demographic information. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Refrigerated | Specimen must be drawn between 14 weeks, 0 days and 24 weeks, 6 days gestation. Separate from cells ASAP or within 2 hours of collection and transfer to standard aliquot tube. See Special Information for list of required patient demographic information. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 72 hours |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 1 year (Avoid repeated freeze/thaw cycles) |
Days Performed
Sun - Sat
Turnaround Time
3 - 4 days
Methodology
| Name | Description |
|---|---|
| Chemiluminescence Immunoassay (CLIA) |
Reference Range
Special Info
Specimen must be drawn between 14 weeks, 0 days and 24 weeks, 6 days gestation. Submit with Order: Patient's date of birth, current weight, due date, dating method (US, LMP), number of fetuses present, patient's race, if the patient was diabetic at the time of conception, if there is a known family history of neural tube defects, if the patient is currently smoking, if the patient is taking valproic acid or carbamazepine (Tegretol), if this is a repeat sample, and the age of the egg donor if an in vitro fertilization. Hemolyzed specimens will be rejected. This test is New York state approved.
Clinical Info
Second-trimester screening test for open neural tube defects.