Dermatomyositis Autoantibody Panel
Test Mnemonic
DERMYO
CPT Codes
- 83516 - QTY (6)
- 86039 - QTY (1)
Aliases
- ANA
- MDA5
- Mi-2
- NXP2
- P155/140
- SAE1
- TIF1-gamma
Includes
- Mi-2 (nuclear helicase protein) Antibody
- P155/140 Antibody
- SAE1 (SUMO activating enzyme) Antibody
- MDA5 (CADM-140) Antibody
- NXP-2 (Nuclear matrix protein-2) Ab
- TIF-1 gamma (155 kDa) Antibody
- Dermatomyositis Interpretive Information
- Antinuclear Antibody (ANA), HEp-2, IgG
- ANA Interpretive Comment
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 4 mL | Serum | SST (Gold) | Refrigerated | Separate serum from cells ASAP or within 2 hours of collection and transfer to standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 3 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | 2 weeks |
| Frozen | 1 year |
| Ambient | 48 hours |
Days Performed
Sun - Sat
Turnaround Time
8 - 19 days
Methodology
| Name | Description |
|---|---|
| Immunoblot (IB), Qualitative | |
| Immunoprecipitation | |
| Semi-Quantitative Indirect Fluorescent Antibody | |
| Qualitative Particle-Based Multianalyte Technology (PMAT) |
Reference Range
| ANA HEp-2 IgG | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| < 1:80 |
Special Info
REFLEX CRITERIA: Antibodies: Mi-2, P155/140, SAE1, MDA5, NXP2, TIF1-gamma, ANA Hemolyzed, hyperlipemic, or icteric specimens will be rejected. Heat-treated or contaminated specimens are unacceptable. This test is New York DOH approved.