Alprazolam
Test Mnemonic
ALPRA
CPT Codes
- 80346/G0480 - QTY (1)
LOINC ®
3312-6
Aliases
- Xanax
Includes
- Alprazolam
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Serum | No additive (Red) | Refrigerated | Do not use serum separator tubes. Predose (trough) draw). Separate serum from cells within 2 hours of collection and transfer to standard aliquot tube. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Plasma | EDTA (Lavender) | Refrigerated | Predose (trough) draw). Separate plasma from cells within 2 hours of collection and transfer to standard aliquot tube. | |
| 2 mL | Plasma | Sodium heparin (Green) | Refrigerated | Predose (trough) draw). Separate plasma from cells within 2 hours of collection and transfer to standard aliquot tube. | |
| 2 mL | Plasma | Potassium oxalate/sodium fluoride (Gray) | Refrigerated | Predose (trough) draw). Separate plasma from cells within 2 hours of collection and transfer to standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 3 years (Avoid repeated freeze/thaw cycles) |
| Ambient | After separation from cells: 1 week |
Days Performed
Tue, Fri
Turnaround Time
2 - 8 days
Methodology
| Name | Description |
|---|---|
| Quantitative Liquid Chromatography - Tandem Mass Spectrometry |
Reference Range
| Alprazolam | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 10 - 100 | ng/mL | Dose-related range: Anxiety: 10 - 40 ng/mL (Dose: 1 - 4 mg/d) | Dose-related range: Phobia & panic: 50 - 100 ng/mL (Dose: 6 - 9 mg/d) | Dose-related range: Toxic: Greater than 100 ng/mL |
Special Info
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Do not use gel separator tubes. Hemolyzed specimens will be rejected. This test is New York DOH approved.
Clinical Info
Optimize drug therapy and monitor patient adherence. Adverse effects may include somnolence, light-headedness and muscle tremors.