Helicobacter pylori Antigen by EIA, Stool
Test Mnemonic
HPYLAG
Primary CPT Codes
- 87338 - QTY (1), Immunoassay, H. pylori
LOINC ®
17780-8
Aliases
- Campylobacter pylori
- H pylori Antigen, fecal
- H. pylori
- Stool kit
- Stool test
- STUL kit
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.1 mL | Stool | Sterile container | Refrigerated | Refrigerated | Non-preserved stool is the only acceptable specimen. Both solid and liquid stools can be tested. Transport promptly to Microbiology. Refrigerated transport is preferred. Alternatively stool can be frozen if delays in transport >72hrs are anticipated. |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | 72 hours |
| Frozen | Until tested |
| Ambient | Unacceptable |
Days Performed
Mon - Fri
Turnaround Time
1 - 4 days
Methodology
| Name | Description |
|---|---|
| Enzyme Immunoassay (EIA) |
Special Info
Avoid ingestion of antimicrobials, proton pump inhibitors and bismuth within 14 days of specimen collection. They may cause false negative results.
Clinical Info
H. pylori is a recognized cause of duodenal ulcer, dyspepsia and chronic active gastritis. This test is used as an aid in the diagnosis of H. pylori infection. For adults <55 yrs of age, the H pylori antigen assay should be used in conjunction with other noninvasive tests such as the H pylori Breath test for diagnosis of infection. In older adults (>55 yrs) or those with alarm symptoms, invasive tests such as endoscopy with biopsy may prove helpful for diagnosis. Culture and histology are orderable options. Serological testing is not recommended. The antigen test can also be used to monitor treatment following antibiotics.