Immunodeficiency (CDC) Panel
Test Mnemonic
IMMDEF
CPT Codes
- 86357 - QTY (1)
- 86359 - QTY (1)
- 86360 - QTY (1)
- 86355 - QTY (1)
Aliases
- Lymphocyte Subsets
Includes
- CD3+ T Cells
- CD3+CD4+ T Cells
- CD3+CD8+ T Cells
- CD19+ B Cells
- CD3-CD16/56+ NK Cells
- CD4/CD8 Ratio
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 4 mL | Whole blood | EDTA (Lavender) | Ambient | Ambient | Deliver specimens to testing laboratory within 24 hours of collection. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Deliver specimens to testing laboratory within 24 hours of collection. |
| Refrigerated | Unacceptable |
| Frozen | Unacceptable |
Days Performed
Mon - Sat
Turnaround Time
1 - 2 days
Special Info
Samples received between 24 and 48 hours of draw time will be performed and reported along with a lymphocyte viability. Samples received between 48 and 72 hours old will performed and reported along with a lymphocyte viability; however, NK results may not be accurate. Recommend obtaining a fresh sample if clinically indicated. Samples that are less than 75% viable will be rejected and a redraw will be requested. Samples received in testing lab beyond 72 hours cannot be performed. Refrigerated samples may give abberant results and will be rejected.
Clinical Info
This is a single platform, 6-color Flow Cytometry assay used to enumerate CD3+ T cells; CD3+CD4+ T cells; CD3+CD8+ T cells; CD19+ B cells; CD3-CD16/56+ NK cells; and CD4/CD8 Ratio in peripheral blood. These lymphocyte subset percentages and counts are used in the monitoring of Immunodeficiency, HIV infection, and other immunologic disorders.