Adenosine Deaminase, RBC
Test Mnemonic
RBCAD
CPT Codes
- 84311 - QTY (1)
LOINC ®
47549-1
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Whole blood | EDTA (Lavender) | Ambient |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Whole blood | Sodium or Lithium heparin (Green) | Ambient |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 15 days |
| Refrigerated | 15 days |
| Frozen | Unacceptable |
Days Performed
Sun, Tue, Thu
Turnaround Time
2 - 5 days
Methodology
| Name | Description |
|---|---|
| Kinetic Spectrophotometry (KS) |
Clinical Info
Adenosine Deaminase (ADA) deficiency is an autosomal recessive disorder of purine metabolism primarily affecting lymphocyte development, viability, and function. Affected individuals have less than 1 percent of normal ADA catalytic activity in red cell hemolysates. ADA deficiency is the cause of 20-30 percent of SCID cases. If the patient has been recently transfused, ADA deficiency may be masked; interpret results with caution. Heterozygotes cannot be identified by this test. If clinical suspicion remains, consider testing to determine the ADA genotype: Severe Combined Immunodeficiency (SCID) Panel, Sequencing and Deletion/Duplication, 19 Genes (ARUP test code 2010219).