Lysosomal Acid Lipase Activity
Test Mnemonic
LALA
CPT Codes
- 82657 - QTY (1)
Aliases
- LAL deficiency
- Lysosomal acid lipase deficiency
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Whole blood | ACD A (Yellow) | Ambient |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Whole blood | EDTA (Lavender) | Ambient | ||
| 1 mL | Whole blood | Sodium heparin (Green) | Ambient | ||
| Two Circles | Dried Blood Spot(DBS) | Filter Paper (Whatman 903 Protein Saver Card) | Ambient | Allow blood to completely air dry before transporting for a minimum of 4 hours to overnight. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | |||||
| One Circle | Allow blood to completely air dry before transporting for a minimum of 4 hours to overnight. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Whole blood: 3 days; DBS: 1 week |
| Refrigerated | Whole blood: 3 days; DBS: 1 week |
| Frozen | Whole blood: Unacceptable; DBS: 1 month |
Days Performed
Varies
Turnaround Time
4 - 11 days
Methodology
| Name | Description |
|---|---|
| Fluorometry (FLM) |
Special Info
Lysosomal acid lipase activity is reported in nanomoles hydrolyzed per hr per DBS punch.
Clinical Info
Evaluation of patients with a clinical presentation suggestive of lysosomal acid lipase deficiency