Polymyositis and Dermatomyositis Panel
Test Mnemonic
MYOSPL
CPT Codes
- 86039 - QTY (1)
- 83516 - QTY (11)
- 86235 - QTY (1)
- 84182 - QTY (3)
Aliases
- ANA
- EJ
- Ha
- Jo-1
- Ks
- MDA5
- Mi-2
- NXP2
- OJ
- P155/140
- PL-7
- PL12
- SAE1
- SRP
- TIF1-gamma
- Zo
Includes
- Jo-1 Antibody, IgG
- PL-7 (threonyl-tRNA synthetase) Antibody
- PL-12 (alanyl-tRNA synthetase) Antibody
- EJ (glycyl-tRNA synthetase) Antibody
- SRP (Signal Recognition Particle) Ab
- OJ (isoleucyl-tRNA synthetase) Antibody
- Mi-2 (nuclear helicase protein) Antibody
- P155/140 Antibody
- SAE1 (SUMO activating enzyme) Antibody
- MDA5 (CADM-140) Antibody
- NXP-2 (Nuclear matrix protein-2) Ab
- TIF-1 gamma (155 kDa) Antibody
- Myositis Interpretive Information
- Antinuclear Antibody (ANA), HEp-2, IgG
- ANA Interpretive Comment
- Ha (tyrosyl-tRNA synthetase) Ab
- Ks (asparaginyl-tRNA synthetase) Ab
- Zo (phenylalanyl-tRNA synthetase) Ab
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 4 mL | Serum | SST (Gold) | Refrigerated | Draw 2 tubes to ensure adequate serum volume. Separate serum from cells ASAP or within 2 hours of collection and transfer to standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 3 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | 2 weeks |
| Frozen | 1 month |
| Ambient | 48 hours |
Days Performed
Sun - Sat
Turnaround Time
8 - 19 days
Methodology
| Name | Description |
|---|---|
| Immunoblot (IB), Qualitative | |
| Immunoprecipitation | |
| Semi-Quantitative Multiplex Bead Assay | |
| Semi-Quantitative Indirect Fluorescent Antibody | |
| Qualitative Particle-Based Multianalyte Technology (PMAT) |
Special Info
REFLEX CRITERIA: Antibodies: PL-7, PL12, EJ, OJ, SRP, Jo-1, Mi-2, P155/140, SAE1, MDA5, NXP2, TIF1-gamma, ANA, Ha, Ks, Zo Hemolyzed, hyperlipemic, or icteric specimens will be rejected. Heat-treated or contaminated specimens are unacceptable. This test is New York DOH approved.