DNAse-B Antibody
Test Mnemonic
DASEAB
CPT Codes
- 86215 - QTY (1)
Aliases
- ADNB
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated | Separate serum from cells ASAP or within 2 hours of collection and transfer to standard aliquot tube |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.4 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 2 hours |
| Refrigerated | After separation from cells: 8 days |
| Frozen | After separation from cells: 3 months |
Days Performed
Sun - Sat
Turnaround Time
2 - 5 days
Methodology
| Name | Description |
|---|---|
| Quantitative Nephelometry |
Special Info
Plasma or severely hemolyzed specimens are unacceptable. This test is New York DOH approved.
Clinical Info
This test is used to confirm current or recent infection with group A Streptococcus in patients suspected of having a nonsuppurative complication such as acute glomerulonephritis (AGN) or acute rheumatic fever (ARF). DNase-B Antibody and Streptolysin O Antibody (ASO) are generally ordered concurrently. Elevated titers of ASO indicate a recent group A Streptococcus infection. AntiDNase B antibodies typically remain elevated longer than ASO and may remain elevated for several months after infection. Patients suspected of having complications related to a recent Streptococcus infection such as AGN or ARF may have elevated anti-DNase B but normal ASO antibody titers. A negative or very low antiDNase B and ASO antibody titers, especially from a specimen tested 2 weeks after a suspected infection, indicates unlikely incidence of a recent Streptococcus infection.