Amiodarone and Metabolite
Test Mnemonic
AMIOD
CPT Codes
- 80151 - QTY (1)
Aliases
- Desethylamiodarone
Includes
- Amiodarone
- N-Desethyl-Amiodarone
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Frozen, Critical | Collect predose (trough) specimen. Separate serum from cells ASAP or within 2 hours of collection and transfer to amber standard transport tube to protect from light. Additional specimens must be submitted when multiple tests are ordered. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Plasma | EDTA (Lavender) | Frozen, Critical | Collect predose (trough) specimen. Separate plasma from cells ASAP or within 2 hours of collection and transfer to amber standard transport tube to protect from light. Additional specimens must be submitted when multiple tests are ordered. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: Unacceptable |
| Refrigerated | After separation from cells: Unacceptable |
| Frozen | After separation from cells: 1 year |
Days Performed
Mon, Tue, Thu, Fri, Sat
Turnaround Time
2 - 8 days
Methodology
| Name | Description |
|---|---|
| Quantitative Liquid Chromatography - Tandem Mass Spectrometry |
Reference Range
| Amiodarone | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Therapeutic Range: 0.5-2.0 µg/mL | Toxic Level: Greater than 2.5 µg/mL |
Special Info
Critical Frozen. Protect from light. Collect predose (trough) draw - at steady state concentration. Additional specimens must be submitted when multiple tests are ordered. This test is New York state approved.
Clinical Info
This test is useful to optimize drug therapy and monitor patient adherence.