Anaplasma phagocytophilum (HGA) Antibodies, IgG and IgM




Test Mnemonic

ANIGM

CPT Codes

  • 86666 - QTY (2)

Aliases

  • HGE
  • Phagocytophilum Titer

Includes

  • Anaplasma phagocytophilum (HGA) Ab, IgG
  • Anaplasma phagocytophilum (HGA) Ab, IgM

Performing Laboratory

ARUP


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumSST (Gold) RefrigeratedSeparate serum from cells ASAP or within 2 hours of collection and transfer into standard aliquot tube. For parallel testing, convalescent specimens must be received within 30 days from receipt of the acute specimens. Label specimens plainly as 'acute' and 'convalescent.'

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.4 mL     

Stability

Environmental Condition Description
AmbientAfter separation from cells: 48 hours
RefrigeratedAfter separation from cells: 2 weeks
FrozenAfter separation from cells: 1 year

Days Performed

Tue, Fri

Turnaround Time

2 - 6 days

Methodology

Name Description
Indirect Fluorescent Antibody (IFA) 

Reference Range

HGA Ab, IgG
Sex Age From Age To Type Range Range Unit
       < 1:80 - No significant level of IgG antibodies to A. phagocyophilum detected. 
       > or = 1:80 - Suggestive of recent or past infection with A. phagocytophilum. 
HGA Ab, IgM
Sex Age From Age To Type Range Range Unit
       < 1:16 - No significant levels of IgM antibodies to A. phagocytophilum detected. 
       > or = 1:16 - Suggestive of current or recent infection with A. phagocytophilum. 

Special Info

Bacterially contaminated, heat-inactivated, hemolyzed, icteric, turbid, or lipemic specimens will be rejected. This test is New York DOH approved.

Clinical Info

Acceptable test for acute or convalescent phase of infection from A. phagocytophilum. May be useful when PCR testing is not an option (e.g., outside the 2 week window for acute phase). However, PCR testing is generally preferred.