Anti-Nuclear Antibodies by IFA, Synovial Fluid




Test Mnemonic

BFANA

CPT Codes

  • 86038 - QTY (1)

LOINC ®

14613-4

Aliases

  • ANA Synovial Fluid

Performing Laboratory

LabCorp


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLFluid, synovialSterile container Frozen 

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.3 mL    Note: This volume does NOT allow for repeat testing.

Stability

Environmental Condition Description
Frozen60 days; Stable x 1 freeze/thaw cycle
Refrigerated14 days
Ambient7 days

Days Performed

Varies

Turnaround Time

6 - 8 days

Methodology

Name Description
Indirect Fluorescent Antibody (IFA) 

Special Info

This test reflexes to ANA Titer and Pattern Synovial Fluid if ANA by IFA is positive in order to rule out false positive ANA by IFA. Bacterial contamination, gross hemolysis, lipemic or icteric specimens, and specimens other than synovial fluid are unacceptable.

Clinical Info

Anti-nuclear antibodies (ANA) are commonly found in a variety of autoimmune diseases. Antibody frequency increases with age in apparently healthy people. ANA patterns on HEp-2 slides provide only general clues about particles (chromatin, nucleosomes,and spliceosomes). ANA patterns (other than centromere pattern) are not reliably correlated with the presence of specific antibodies and must be further evaluated by enzyme immunoassay using individual ENA antigens.