FISH for CBFB/MYH11 Blood




Test Mnemonic

INV16F

CPT Codes

  • 88271 - QTY (2)
  • 88275 - QTY (1)
  • 88291 - QTY (1)
  • 88237 - QTY (1)

Aliases

  • FISH for inv(16)
  • FISH testing for AML, FAB-M4Eo
  • Fluorescence In Situ Hybridization for inv(16)(p13

Includes

  • Result

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
5 - 7 mLBlood, peripheralEDTA (Lavender)AmbientAmbient 

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
5 - 7 mLBlood, peripheralSodium heparin (Green)AmbientAmbient 

Stability

Environmental Condition Description
Ambient40 hours
RefrigeratedAcceptable
FrozenNot acceptable

Days Performed

4 days per week

Turnaround Time

5 - 7 days

Methodology

Name Description
Fluorescent In-Situ Hybridization (FISH) 

Clinical Info

To assist in the diagnosis of acute myelocytic leukemia, specifically acute myelomonocytic leukemia. This chromosome abnormality is usually associated with increased number of immature eosinophils in the bone marrow and often with peripheral blood eosinophilia.