FISH for CBFB/MYH11 Blood
Test Mnemonic
INV16F
CPT Codes
- 88271 - QTY (2)
- 88275 - QTY (1)
- 88291 - QTY (1)
- 88237 - QTY (1)
Aliases
- FISH for inv(16)
- FISH testing for AML, FAB-M4Eo
- Fluorescence In Situ Hybridization for inv(16)(p13
Includes
- Result
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 - 7 mL | Blood, peripheral | EDTA (Lavender) | Ambient | Ambient |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 - 7 mL | Blood, peripheral | Sodium heparin (Green) | Ambient | Ambient |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 40 hours |
| Refrigerated | Acceptable |
| Frozen | Not acceptable |
Days Performed
4 days per week
Turnaround Time
5 - 7 days
Methodology
| Name | Description |
|---|---|
| Fluorescent In-Situ Hybridization (FISH) |
Clinical Info
To assist in the diagnosis of acute myelocytic leukemia, specifically acute myelomonocytic leukemia. This chromosome abnormality is usually associated with increased number of immature eosinophils in the bone marrow and often with peripheral blood eosinophilia.