FISH for PDGFRB Rearrangement Bone Marrow




Test Mnemonic

PDGFBM

CPT Codes

  • 88271 - QTY (2)
  • 88275 - QTY (1)
  • 88291 - QTY (1)
  • 88237 - QTY (1)

Aliases

  • FISH for PDGFRB
  • Imatinib Mesylate Responsive Gene
  • PDGFR beta

Includes

  • FISH for PDGFRB (5q32)

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 - 3 mLBone marrowEDTA (Lavender)AmbientAmbient 

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 - 3 mLBone marrowSodium heparin (Green)AmbientAmbient 

Stability

Environmental Condition Description
Ambient48 hours
RefrigeratedAcceptable
FrozenNot acceptable

Days Performed

5 days per week

Turnaround Time

5 - 7 days

Methodology

Name Description
Fluorescent In-Situ Hybridization (FISH) 

Clinical Info

A dual color, break-apart probe flanking the centromeric and telomeric sides of the PDGFRB (5q32) locus is used to evaluate for a translocation involving the PDGFRB gene. If no cells are available for analysis, no analysis charges will be incurred.