Ganglioside (GM1) Antibodies, IgG and IgM
Test Mnemonic
GM1ABP
CPT Codes
- 83516 - QTY (2)
Includes
- GM1 Antibody IgG
- GM1 Antibody IgM
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.3 mL | Serum | SST (Gold) | Refrigerated | Separate serum from cells ASAP or within 2 hours of collection and transfer to standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Unacceptable |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 1 year |
Days Performed
Tue, Thu, Sat
Turnaround Time
2 - 8 days
Methodology
| Name | Description |
|---|---|
| Semi Quantitative Enzyme Linked Immunosorbent Assay |
Special Info
Unacceptable conditions: heat inactivated, severely lipemic, contaminated or hemolyzed specimens.
Clinical Info
Elevated antibody levels to ganglioside-monosialic acid (GM1) are associated with motor or sensorimotor neuropathies, particularly multifocal motor neuropathy. Anti-GM1 may occur as IgM (polyclonal or monoclonal) or IgG antibodies. These antibodies may also be found in patients with diverse connective tissue diseases as well as normal individuals. These tests by themselves are not diagnostic and should be used in conjunction with other clinical parameters to confirm disease.