Glutathione Total
Test Mnemonic
GLUTAT
CPT Codes
- 82978 - QTY (1)
LOINC ®
2383-8
Includes
- Glutathione Total
Performing Laboratory
LabCorp
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | Blood | ACD A or B (Yellow) | Ambient | Allow ACD tubes to fill completely; gently invert 8-10 times (do not shake). |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 2 weeks |
| Refrigerated | 2 weeks |
| Frozen | 1 week |
Days Performed
Mon - Fri
Turnaround Time
5 - 8 days
Methodology
| Name | Description |
|---|---|
| Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) |
Special Info
Hemolyzed and clotted specimens are unacceptable.
Clinical Info
Glutathione is a tripeptide and is the primary regulator of cellular redox states. Glutathione exists primarily in its reduced form (GSH), which upon oxidation forms the dimer, glutathione disulfide (GSSG). GSH can also form disulfide bridges with proteins as a result of oxidation or enzyme catalyzed reactions, giving rise to protein-bound glutathione (GSSP). Decreased glutathione levels in whole blood have been associated with Parkinson's disease, HIV, liver disease, renal failure, as well as preëclampsia. Results of this test are for investigational purposes only. The performance characteristics of this assay have been determined by the performing laboratory. The result should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.