Glutathione Total




Test Mnemonic

GLUTAT

CPT Codes

  • 82978 - QTY (1)

LOINC ®

2383-8

Includes

  • Glutathione Total

Performing Laboratory

LabCorp


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mLBloodACD A or B (Yellow) AmbientAllow ACD tubes to fill completely; gently invert 8-10 times (do not shake).

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.1 mL     

Stability

Environmental Condition Description
Ambient2 weeks
Refrigerated2 weeks
Frozen1 week

Days Performed

Mon - Fri

Turnaround Time

5 - 8 days

Methodology

Name Description
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) 

Special Info

Hemolyzed and clotted specimens are unacceptable.

Clinical Info

Glutathione is a tripeptide and is the primary regulator of cellular redox states. Glutathione exists primarily in its reduced form (GSH), which upon oxidation forms the dimer, glutathione disulfide (GSSG). GSH can also form disulfide bridges with proteins as a result of oxidation or enzyme catalyzed reactions, giving rise to protein-bound glutathione (GSSP). Decreased glutathione levels in whole blood have been associated with Parkinson's disease, HIV, liver disease, renal failure, as well as pre√ęclampsia. Results of this test are for investigational purposes only. The performance characteristics of this assay have been determined by the performing laboratory. The result should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.