Glutathione Total
Test Mnemonic
GLUTAT
CPT Codes
- 82978 - QTY (1)
LOINC ®
2383-8
Includes
- Glutathione Total
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 10 mL | Whole blood | ACD B (Yellow) | Place specimen on ice after draw. | Refrigerated | ACD tube must be filled greater than 50% of total volume to maintain ratio of blood-to-liquid anticoagulant. Critical Refrigerated. Transport whole blood in original collection container or transfer at least 1 mL to standard aliquot tube. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 8.5 mL | Whole blood | ACD A (Yellow) | Place specimen on ice after draw. | Refrigerated | ACD tube must be filled greater than 50% of total volume to maintain ratio of blood-to-liquid anticoagulant. Critical Refrigerated. Transport whole blood in original collection container or transfer at least 1 mL to standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 8.5 mL | Collection tube must be filled greater than 50% of total volume to maintain ratio of blood-to-liquid anticoagulant. Critical Refrigerated. Transport whole blood in original collection container or transfer at least 1 mL to standard aliquot tube. | ||||
| 6.5 mL | Collection tube must be filled greater than 50% of total volume to maintain ratio of blood-to-liquid anticoagulant. Critical Refrigerated. Transport whole blood in original collection container or transfer at least 1 mL to standard aliquot tube. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Unacceptable |
| Refrigerated | 3 weeks |
| Frozen | Unacceptable |
Days Performed
Varies
Turnaround Time
6 - 10 days
Methodology
| Name | Description |
|---|---|
| Quantitative, Kinetic |
Reference Range
Special Info
Collection tube must be filled greater than 50% of total volume. This test is New York state approved.
Clinical Info
Glutathione is a tripeptide and is the primary regulator of cellular redox states. Glutathione exists primarily in its reduced form (GSH), which upon oxidation forms the dimer, glutathione disulfide (GSSG). GSH can also form disulfide bridges with proteins as a result of oxidation or enzyme catalyzed reactions, giving rise to protein-bound glutathione (GSSP). Decreased glutathione levels in whole blood have been associated with Parkinson's disease, HIV, liver disease, renal failure, as well as preëclampsia. Results of this test are for investigational purposes only. The performance characteristics of this assay have been determined by the performing laboratory. The result should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.