Human Epididymis Protein 4
Test Mnemonic
HEP4
CPT Codes
- 86305 - QTY (1)
LOINC ®
55180-4
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Refrigerated |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 24 hours |
| Refrigerated | 7 days |
| Frozen | 14 days |
Days Performed
Mon, Wed, Fri
Turnaround Time
1 - 4 days
Methodology
| Name | Description |
|---|---|
| Chemiluminescent Microparticle Immunoassay (CMIA) |
Reference Range
| Human Epididymis Protein 4 | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Female | Years | 99 Years | Normal | Premenopausal <=70 | pmol/L | Female | Years | 99 Years | Normal | Postmenopausal <=140 | pmol/L | Male | Years | 99 Years | Normal | Not applicable | . |
Special Info
The Human Epididymis Protein 4 Antigen test was performed using the Abbott Alinity chemiluminescent microparticle immunoassay method. Results obtained with different assay methods or kits cannot be used interchangeably.
Clinical Info
HE4 test is used as in aid in monitoring of progression or recurrence of disease in patients with established diagnosis of ovarian carcinoma. The test should not be used for screening. Final interpretation requires correlation with clinical picture and other diagnostic modalities. Specimens from patients who have received preparations of mouse monoclonal antibodies for diagnosis or therapy may contain human anti-mouse antibodies (HAMA). Specimens containing HAMA may produce anomalous values when tested by this assay.
Clinical Limitation
Criteria for rejection: Heat inactivated, pooled, grossly hemolyzed, obvious microbial contamination, cadaver samples or body fluids other than human serum.