Hyperoxaluria, Urine
Test Mnemonic
UHYPER
CPT Codes
- 82542 - QTY (1)
Includes
- Glycolate
- Glycerate
- Oxalate
- Interpretation
- 4-Hydroxy-2-Oxoglutarate
Performing Laboratory
Mayo Clinic Dpt of Lab Med & Pathology
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 10 mL | Urine, random | Clean container | Frozen | Overnight fast is required: 1) Have patient discard the first-morning void. 2) Collect specimen within 2 hours of first-morning void while patient continues to fast. Fluids are allowed. 3) Freeze the specimen immediately. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1.1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Frozen | 90 days |
| Ambient | Unacceptable |
| Refrigerated | 14 days |
Days Performed
Varies; 2 times per month
Turnaround Time
15-31 days
Methodology
| Name | Description |
|---|---|
| GC-MS Stable Isotope Dilution Analysis |
Special Info
Informed consent is required for patients residing in New York State. Specimens with preservatives will be rejected.
Clinical Info
Increased concentrations of oxalate and glycolate indicate type 1 hyperoxaluria. Increased concentrations of oxalate and glycerate indicate type 2 hyperoxaluria. Increased concentrations of oxalate and 4-hydroxy-2-oxoglutarate indicate type 3 hyperoxaluria. Increased concentrations of oxalate with normal concentrations of glycolate, glycerate, and 4-hydroxy-2-oxoglutarate indicate secondary hyperoxaluria.