Lactate Dehydrogenase, Body Fluid




Test Mnemonic

BFLDH

CPT Codes

  • 83615 - QTY (1)

LOINC ®

2529-6

Aliases

  • LD Body Fluid

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLFluid, bodySterile container AmbientViscous specimens will be rejected. Indicate source of fluid.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mL     

Stability

Environmental Condition Description
Ambient5 days
Refrigerated2 days
FrozenUnacceptable

Days Performed

Sun - Sat

Turnaround Time

8 hours

Methodology

Name Description
Enzymatic 

Reference Range

Lactate Dehydrogenase, Body Fluid
Sex Age From Age To Type Range Range Unit
       Refer to Clinical Information 

Special Info

Indicate body fluid source/type.

Clinical Info

Pleural fluids: Pleural fluid lactate dehydrogenase (LDH) measurements may be useful for classifying pleural effusions as exudates. A ratio of pleural fluid LDH to a concurrent serum LDH > 0.6 is suggestive of an exudate. Peritoneal fluids: Ascitic fluid LDH measurements may aid in in characterizing secondary peritonitis and should be interpreted along with other clinical and laboratory information. Synovial fluids: Synovial fluid LDH measurements may be useful as an inflammatory marker for various arthritic conditions and should be interpreted along with other clinical and laboratory information. References: 1. CLSI. Analysis of Body Fluids in Clinical Chemistry; Approved Guideline. CLSI document C49-A. Wayne, PA: Clinical Laboratory Standards Institute; 2007. 2. Block DR, Algeciras-Schimnich A. Body fluid analysis: clinical utility and applicability of published studies to guide interpretation of today’s laboratory testing in serous fluids. Crit Rev Clin Lab Sci, 2013;50(4-5):107-124. 3. Pejovic M, Stankovic A, Mitrovic DR. Lactate dehydrogenase activity and its isoenzymes in serum and synovial fluid of patients with rheumatoid arthritis and osteoarthritis. J Rheumatol. 1992;19:529-533.

Clinical Limitation

In connection with certain diseases (e.g. hepatopathy, diseases of skeletal muscles, malignant tumors), the LDH-4 and LDH-5 isoenzyme portions are increased and unstable in cooled and frozen samples; this may lead to an incorrect LDH value in samples collected from patients suffering from such diseases.