Lactate Dehydrogenase, Body Fluid
Test Mnemonic
BFLDH
CPT Codes
- 83615 - QTY (1)
LOINC ®
2529-6
Aliases
- LD Body Fluid
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Fluid, body | Sterile container | Ambient | Viscous specimens will be rejected. Indicate source of fluid. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 5 days |
| Refrigerated | 2 days |
| Frozen | Unacceptable |
Days Performed
Sun - Sat
Turnaround Time
8 hours
Methodology
| Name | Description |
|---|---|
| Enzymatic |
Reference Range
| Lactate Dehydrogenase, Body Fluid | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Refer to Clinical Information |
Special Info
Indicate body fluid source/type.
Clinical Info
Pleural fluids: Pleural fluid lactate dehydrogenase (LDH) measurements may be useful for classifying pleural effusions as exudates. A ratio of pleural fluid LDH to a concurrent serum LDH > 0.6 is suggestive of an exudate. Peritoneal fluids: Ascitic fluid LDH measurements may aid in in characterizing secondary peritonitis and should be interpreted along with other clinical and laboratory information. Synovial fluids: Synovial fluid LDH measurements may be useful as an inflammatory marker for various arthritic conditions and should be interpreted along with other clinical and laboratory information. References: 1. CLSI. Analysis of Body Fluids in Clinical Chemistry; Approved Guideline. CLSI document C49-A. Wayne, PA: Clinical Laboratory Standards Institute; 2007. 2. Block DR, Algeciras-Schimnich A. Body fluid analysis: clinical utility and applicability of published studies to guide interpretation of today’s laboratory testing in serous fluids. Crit Rev Clin Lab Sci, 2013;50(4-5):107-124. 3. Pejovic M, Stankovic A, Mitrovic DR. Lactate dehydrogenase activity and its isoenzymes in serum and synovial fluid of patients with rheumatoid arthritis and osteoarthritis. J Rheumatol. 1992;19:529-533.
Clinical Limitation
In connection with certain diseases (e.g. hepatopathy, diseases of skeletal muscles, malignant tumors), the LDH-4 and LDH-5 isoenzyme portions are increased and unstable in cooled and frozen samples; this may lead to an incorrect LDH value in samples collected from patients suffering from such diseases.