Macroprolactin




Test Mnemonic

MACPRO

CPT Codes

  • 84146 - QTY (2)

Aliases

  • Macroprolactin by PEG
  • Macroprolactin by PEG

Performing Laboratory

ARUP


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumSST (Gold) FrozenAllow specimen to clot completely at room temperature. Separate serum from cells and transfer into standard aliquot tube.

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLPlasmaLithium heparin PST (Lt. Green) FrozenSeparate plasma from cells and transfer into standard aliquot tube.
1 mLPlasmaEDTA (Lavender) FrozenSeparate plasma from cells and transfer into standard aliquot tube.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mL     

Stability

Environmental Condition Description
FrozenAfter separation from cells: 1 month
RefrigeratedAfter separation from cells: 7 days
AmbientAfter separation from cells: 8 hours

Days Performed

Sun

Turnaround Time

2 - 9 days

Methodology

Name Description
Chemiluminescence Immunoassay (CLIA) 

Reference Range

Monomeric Prolactin
Sex Age From Age To Type Range Range Unit
Male1 Years9 YearsNormal2.1 - 13.3ng/mL
Male10 Years99 YearsNormal2.1 - 13.3ng/mL
Female1 Years9 YearsNormal2.1 - 13.3ng/mL
Female10 Years99 YearsNormal2.8 - 19.5ng/mL
Monomeric Prolactin Percent
Sex Age From Age To Type Range Range Unit
       Greater than 50% 
Prolactin
Sex Age From Age To Type Range Range Unit
Male1 Years9 YearsNormal2.1 - 17.7ng/mL
Male10 Years99 YearsNormal2.1 - 17.7ng/mL
Female1 Years9 YearsNormal2.1 - 17.7ng/mL
Female10 Years99 YearsNormal2.8 - 29.2ng/mL

Special Info

Allow serum specimen to clot completely at room temperature.

Clinical Info

If the % Monomeric Prolactin is 40-50%, then the result is indeterminate for macroprolactin. If the % Monomeric Prolactin is less than 40%, then this indicates the presence of macroprolactin. A Monomeric Prolactin result above the upper reference limit is consistent with hyperprolactinemia. Monomeric Prolactin was determined by PEG precipitation. Macroprolactin is precipitated by PEG and is not measured.