MYD88 L265P Mutation Analysis
Test Mnemonic
MYD88
CPT Codes
- 81305 - QTY (1)
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 4 mL | Whole blood | EDTA (Lavender) | Ambient | Refrigerated | Aliquots not accepted. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | whole blood. Aliquots not accepted. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | blood: 48 hours |
| Refrigerated | blood: 7 days |
| Frozen | blood: unacceptable |
Days Performed
3 days per week
Turnaround Time
5 days
Methodology
| Name | Description |
|---|---|
| Droplet Digital Polymerase Chain Reaction (PCR) |
Reference Range
| MYD88 L265P MUTATION RESULT | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | Refer to report |
Special Info
Ambient up to 24 hours. Refrigerated up to 7 days. Aliquots not accepted.
Clinical Info
This test is designed to detect the point mutation c.794T>C, p.L265P in the MYD88 gene. MYD88 L265P mutations are present in the majority of cases of lymphoplasmacytic lymphoma and, less commonly, in other B-cell lymphoproliferative disorders.