Oxidized Low-density Lipoprotein (OxLDL)
Test Mnemonic
OXLDL
CPT Codes
- 83721 - QTY (1)
Includes
- Oxidized LDL
Performing Laboratory
LabCorp
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | Plasma | EDTA (Lavender) | Frozen, Critical | CRITICAL FROZEN. Gently invert tube 8 to 10 times then centrifuge and aliquot approximately 2/3 of the upper plasma layer into a standard aliquot tube within 45 minutes of collection. Separate specimens must be submitted when multiple tests are ordered. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.2 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | Unacceptable |
| Frozen | 2 years (1 freeze/thaw cycle) |
| Ambient | Unacceptable |
Days Performed
Varies
Turnaround Time
4 - 6 days
Methodology
| Name | Description |
|---|---|
| Enzyme-Linked Immunosorbent Assay (ELISA) |
Special Info
CRITICAL FROZEN. Lipemic or hemolyzed specimens will be rejected. Separate specimens must be submitted when multiple tests are ordered.
Clinical Info
This test is useful in the diagnosis and treatment of lipid disorders (such as diabetes mellitus), atherosclerosis, and various liver and renal diseases, especially as it pertains to the evaluation of oxidative stress. Oxidized LDL-particles are considered to be an important driving factor in the pathophysiology of atherosclerosis and oxLDL measurement has been used to test the efficacy of CVD drugs (eg, statins) to reduce oxidative stress.