Phospholipase A2 Receptor IgG Antibody ELISA
Test Mnemonic
PLA2R
CPT Codes
- 83520 - QTY (1)
Aliases
- PLA2R
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | Red Plain | Refrigerated |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 24 hours |
| Refrigerated | 14 days |
| Frozen | 30 days |
Days Performed
Mon, Wed, Fri
Turnaround Time
2 - 4 days
Methodology
| Name | Description |
|---|---|
| Enzyme-Linked Immunosorbent Assay (ELISA) |
Clinical Limitation
The test is not a standalone test but an adjunct to other clinical information. A diagnosis of pMN should not be made on a single test result. The clinical symptoms, results on physical examination, and laboratory tests (e.g., serological tests), when appropriate, should always be taken into account when considering the diagnosis of primary versus secondary MN. Absence of circulating PLA2R autoantibodies does not rule out a diagnosis of PLA2R-related membranous nephropathy. Clinical evidence must not be overruled in favor of a numerical value. The assay has not been demonstrated to be effective for monitoring the stage of disease or its response to treatment.