Polymyositis Panel
Test Mnemonic
POLMYO
CPT Codes
- 83516 - QTY (5)
- 86235 - QTY (1)
- 84182 - QTY (3)
- 86039 - QTY (1)
Aliases
- ANA
- EJ
- Ha
- Jo-1
- Ks
- OJ
- PL-7
- PL12
- SRP
- Zo
Includes
- Jo-1 (Histidyl-tRNA Synthetase) Ab, IgG
- PL-7 (threonyl-tRNA synthetase) Antibody
- PL-12 (alanyl-tRNA synthetase) Antibody
- EJ (glycyl-tRNA synthetase) Antibody
- SRP (Signal Recognition Particle) Ab
- OJ (isoleucyl-tRNA synthetase) Antibody
- Polymyositis Interpretive Information
- Antinuclear Antibody (ANA), Hep-2, IgG
- ANA Interpretive Comment
- Ha (tyrosyl-tRNA synthetase) Ab
- Ks (asparaginyl-tRNA synthetase) Ab
- Zo (phenylalanyl-tRNA synthetase) Ab
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 4 mL | Serum | SST (Gold) | Refrigerated | Draw 2 tubes to ensure adequate serum volume. Separate serum from cells ASAP or within 2 hours of collection and transfer to standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 3 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | 2 weeks |
| Frozen | 1 month |
| Ambient | 48 hours |
Days Performed
Mon, Tue, Thu, Fri
Turnaround Time
8 - 19 days
Methodology
| Name | Description |
|---|---|
| Immunoprecipitation | |
| Semi-Quantitative Multiplex Bead Assay | |
| Immunoblot (IB), Qualitative | |
| Semi-Quantitative Indirect Fluorescent Antibody |
Reference Range
| Antinuclear Ab (ANA) HEp-2 IgG | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| < 1:80 | |||||
| Jo-1 Antibody, IgG | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| 0 - 40 AU/mL |
Special Info
REFLEX CRITERIA: Antibodies: PL-7, PL12, EJ, OJ, SRP, Jo-1, ANA, Ha, Ks, Zo Hemolyzed, hyperlipemic, or icteric specimens will be rejected. Heat-treated or contaminated specimens are unacceptable. This test is New York DOH approved.
Clinical Info
This test may be useful for the evaluation of patients with progressive proximal muscle weakness and antisynthetase syndrome.