Procainamide/NAPA
Test Mnemonic
PROC
CPT Codes
- 80192 - QTY (1)
LOINC ®
3983-4
Aliases
- N-Acetylprocainamide
- Pronestyl
Includes
- N Acetylprocainamide
- Procainamide
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Centrifuge, aliquot and refrigerate ASAP. | Collect immediately prior to next dose. Do not use serum separator tubes. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Plasma | Lithium heparin (Green) | Centrifuge, aliquot and refrigerate ASAP. | Collect immediately prior to next dose. Do not use plasma separator tubes. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 16 hours |
| Refrigerated | After separation from cells: 6 days |
| Frozen | After separation from cells: 6 months |
Days Performed
Mon - Sat
Turnaround Time
1 - 2 days
Methodology
| Name | Description |
|---|---|
| Enzyme Immunoassay (EIA) |
Reference Range
| N Acetylprocainamide | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | Years | Normal | 6.0 - 20.0 | ug/mL | Years | Years | Urgent | > 35.0 | ug/mL |
| Procainamide | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | Years | Normal | 4.0 - 10.0 | ug/mL | Years | Years | Urgent | > 12.0 | ug/mL |
Special Info
Collect immediately prior to next dose. Do not use serum separator tubes.
Clinical Info
The commonly expected therapeutic range for the sum of NAPA and Procainamide is 5-30 ug/mL. However, the concentration of NAPA is dependent on many factors, including; time of last procainamide dose, mode of administration, concomitant drug therapy, sample condition, time of sample collection and individual variations in absorption, biotransformation, distribution and excretion. Therapeutic ranges are provided only as a guide for interpretation along with other clinical symptoms and patient history.