Protein S Clottable




Test Mnemonic

PRSCLT

CPT Codes

  • 85306 - QTY (1)

LOINC ®

27822-6

Aliases

  • Pro S Functional

Performing Laboratory

n/a


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 mLPlasmaSodium citrate (Lt. Blue) Frozen 

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mL     

Days Performed

Mon - Fri

Turnaround Time

1 - 3 days

Methodology

Name Description
Clotting Assay 

Reference Range

Protein S Clottable
Sex Age From Age To Type Range Range Unit
   Days1 DaysNormal14-90%
 2 Days5 DaysNormal14-90%
 6 Days30 DaysNormal14-90%
 1 Months3 MonthsNormal49-114%
 4 Months11 MonthsNormal50-116%
 1 Years5 YearsNormal43-167%
 6 Years10 YearsNormal45-150%
 11 Years16 YearsNormal53-133%
 17 Years999 YearsNormal59-152%

Special Info

3.2% sodium citrate is the preferred anticoagulant recommended by CLSI. If protein S clottable is decreased, suggest ordering factor VIII, APC - R and protein S immunologic.

Clinical Info

For use in the evaluation of hypercoagulable state due to congenital or acquired protein S deficiency. This is a functional assay which detects the amount of Protein S in plasma. Coumadin will lower protein S levels. Elevated factor VIII levels (>250%) and APC resistance (factor V Leiden) can lower protein S clottable. High heparin concentration (> 1 unit/ mL) and lupus anticoagulant can falsely elevate protein S clottable.

Clinical Limitation

n/a

Clinical Reference

n/a