Fungal Susceptibility - yeast
Test Mnemonic
FUNSUS
CPT Codes
- 87186 - QTY (1)
Aliases
- Yeast Susceptibility
- Yeast MIC
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| Variable | Isolate of organism | Agar slant | Ambient | Pure isolates of a single organism should be sent on an agar slant at ambient temperatures. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 4 weeks |
| Refrigerated | 4 weeks |
| Frozen | Unacceptable |
Days Performed
Sun - Sat
Turnaround Time
11 days
Methodology
| Name | Description |
|---|---|
| Microtiter Dilution |
Reference Range
Special Info
Yeast susceptibility testing is determined by colorimetric microdilution broth. A standardized inoculation of test organism is incubated with appropriate dilutions of antifungal agents; minimum inhibitory concentration (MIC) are determined by inhibition of growth at the lowest antifungal concentration. MIC are determined and interpreted according to CLSI standards. Mold susceptibility testing is not performed in-house but is available as a send out test. Indicate organism identification, original date of collection, and specimen site on the test order. Submit a pure culture of the test organism. Contraindications: lack of viability, culture mixed or contaminated or wrong ID will incur extra charges or result in cancellation of the test. Note specific drug requests on the requisition.
Clinical Info
Useful for determining in vitro minimal inhibitory concentrations of non-fastidious yeast. Susceptibility testing can aid in management due to recurrent infections, invasive infections and where certain antifungals are contraindicated
Clinical Limitation
CLSI guidelines are available only for the interpretation of Candida species susceptibility test results. In vitro studies may not correlate with clinical outcome.