Platelet Assoc. Abs. IgG, IgM
Test Mnemonic
PLTABD
CPT Codes
- 86023 - QTY (2)
Aliases
- Platelet Antibodies, Direct
Includes
- IgG Antibody
- IgM Antibody
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 10 mL | Whole blood | EDTA (Lavender) | Ambient | Send to Cleveland Clinic Laboratories on the day of collection. Specimens must be received by 3:00 p.m. Monday - Thursday and by 1:00 p.m. on Friday on the day of collection. Do not draw on a holiday or on the day before a holiday. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 2 days |
| Refrigerated | Unacceptable |
| Frozen | Unacceptable |
Days Performed
Sun - Sat
Turnaround Time
3 - 4 days
Reference Range
Special Info
Specimens MUST be analyzed at the performing laboratory within 48 hours of collection. Critical Ambient. Required amount of blood may be dependent on platelet count.
Clinical Info
Detect antibodies which cause platelet destruction. Detection of platelet-associated IgG and/or IgM may be used to separate thrombocytopenia of immune origin from nonimmune origin. Most patients with ITP have abnormally high levels of IgG associated with their platelets. Occasionally patients will have normal IgG levels but abnormally high levels of IgM. Dual staining and flow cytometric analysis ensures that only platelets are analyzed and relatively small volumes of blood are required. This assay does not distinguish between autoantibodies and alloantibodies, nor does it identify specific types of antiplatelet antibodies, such as those against HPA-1a.