5-Methyltetrahydrofolate




Test Mnemonic

5MTH

CPT Codes

  • 82542 - QTY (1)

Performing Laboratory

Medical Neurogenetics


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
4.5 mLCerebrospinal fluid (CSF)Set of 5 MNG Collection Tubes FrozenCSF should be collected from the first drop into the containers in the order indicated. Fill each tube to the marked line (0.5 mL in tube 1; 1.0 mL in tubes 2, 3, 4, and 5). Place specimens on ice after collection. If specimen is blood contaminated, the tubes should immediately be centrifuged (prior to freezing) and the clear CSF transferred to new similarly labeled tubes then frozen ASAP at -80 C. Call Client Services at 800-628-6216 to obtain appropriate specimen collection containers.

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLCerebrospinal fluid (CSF)Clean containerFrozen This specimen to be used if 5-MTH is the only CSF Medical Neurogenetics test ordered.

Stability

Environmental Condition Description
AmbientUnacceptable
FrozenIndefinitely
RefrigeratedUnacceptable

Days Performed

Tue - Fri

Turnaround Time

15 - 17 days

Methodology

Name Description
High Performance Liquid Chromatography with Electrochemical Detection 

Reference Range

5-Methyltetrahydrofolate
Sex Age From Age To Type Range Range Unit
   Months6 MonthsNormal40 - 240nmol/L
 6 Months24 MonthsNormal40 - 187nmol/L
 2 Years5 YearsNormal40 - 150nmol/L
 5 Years10 YearsNormal40 - 128nmol/L
 10 Years99 YearsNormal40 - 120nmol/L

Special Info

Prior to collecting sample, contact Client Services to obtain sample collection containers consisting of 5 numbered tubes per set. CSF should be collected from the first drop into the containers in the order indicated. Fill each tube to the marked line (0.5 mL in tube 1; 1.0 mL in tubes 2, 3, 4, and 5). Tube #3 contains antioxidants to protect the sample from oxidation. One set of vials is required per patient.

Clinical Info

Cerebral Folate deficiency