Adenovirus Quantitative Real-time PCR




Test Mnemonic

ADVQNT

CPT Codes

  • 87799 - QTY (1)

Performing Laboratory

ViraCor-IBT Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 mLPlasmaEDTA (Lavender) FrozenDo not use gel separator tubes. Transfer plasma to standard aliquot tube.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mL     

Stability

Environmental Condition Description
Frozen2 weeks
Ambient4 days
Refrigerated4 days

Days Performed

Mon - Sat

Turnaround Time

2 - 3 days

Methodology

Name Description
Real-Time Polymerase Chain Reaction (RT-PCR) 

Clinical Info

Adenovirus is an important cause of morbidity and mortality in the transplant setting, causing pneumonia, hemorrhagic cystitis, hepatitis, encephalitis, pancreatitis, enteritis, and disseminated disease with the mortality rate reaching 60% in some especially high risk situations such as pediatric hematopoietic stem cell transplantation. Since proper management is dependent upon early diagnosis, quantitative adenovirus DNA PCR is useful for detecting the virus, tracking the course of infection, and monitoring response to treatment. Treatment of adenovirus in immunocompromised patients presents challenges, including drug toxicity, delayed onset of disease after discontinuing therapy, and emergence of mutations that may affect the ability of diagnostic assays to detect them efficiently.