Antithrombin Assay




Test Mnemonic

AT3ASY

CPT Codes

  • 85300 - QTY (1)

LOINC ®

27811-9

Aliases

  • AT Assay

Performing Laboratory

n/a


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 mLPlasmaSodium citrate (Lt. Blue) Frozen 

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mL     

Stability

Environmental Condition Description
Ambient4 hours
RefrigeratedUnacceptable
Frozen14 days at -20 C; 6 months at -70 C

Days Performed

Mon - Fri

Turnaround Time

1 - 3 days

Methodology

Name Description
Chromogenic 

Reference Range

Antithrombin Assay
Sex Age From Age To Type Range Range Unit
   Days1 DaysNormal42 - 92%
 2 Days5 DaysNormal44 - 98%
 6 Days30 DaysNormal51 - 114%
 1 Months3 MonthsNormal78 - 128%
 4 Months11 MonthsNormal89 - 131%
 1 Years5 YearsNormal93 - 152%
 6 Years10 YearsNormal102 - 144%
 11 Years16 YearsNormal87 - 145%
 17 Years99 YearsNormal84 - 138%

Special Info

3.2% sodium citrate is the preferred anticoagulant recommended by CLSI. Formerly called Antithrombin III Assay.

Clinical Info

(1) Evaluation of the hypercoagulable state to detect congenital and acquired antithrombin deficiency.(2) Useful in diagnosing disseminated intravascular coagulation.(3) Following the response to therapy with antithrombin concentrates.(4) Evaluation of heparin resistance. Patients with antithrombin levels < 65% may have an inadequate clinical response to heparin. Heparin therapy decreases levels to a variable degree.

Clinical Limitation

n/a

Clinical Reference

n/a