Beta-2-Glycoprotein IgG and IgM




Test Mnemonic

B2GPGM

CPT Codes

  • 86146 - QTY (2)

Aliases

  • Beta-2-GPI

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 mLSerumSST (Gold) Refrigerated 

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mL     

Stability

Environmental Condition Description
Ambient1 day
Refrigerated7 days
Frozen1 year, up to 2 freeze thaw cycles

Days Performed

Mon - Fri

Turnaround Time

1 - 3 days

Methodology

Name Description
Enzyme Immunoassay (EIA) 

Reference Range

Beta-2 Glycoprotein, IgG
Sex Age From Age To Type Range Range Unit
   Years99 YearsNormalNegative: < 20SGU
   Years99 YearsNormalLow Positive: 20 - 80SGU
   Years99 YearsNormalHigh Positive: > 80SGU
Beta-2 Glycoprotein, IgM
Sex Age From Age To Type Range Range Unit
   Years99 YearsNormalNegative: < 20SMU
   Years99 YearsNormalLow Positive: 20 - 80SMU
   Years99 YearsNormalHigh Positive: > 80SMU

Clinical Info

Beta-2 GP autoantibodies are found in patients with antiphospholipid syndrome (APS) and are associated with increased risk of venous and arterial thrombosis and thrombocytopenia. Beta-2 GP autoantibodies are found only in patients with autoimmune diseases, while cardiolipin autoantibodies can be transiently found in infectious disease.