Beta-2 Transferrin
Test Mnemonic
B2TRAN
CPT Codes
- 86335 - QTY (1)
LOINC ®
13876-8
Aliases
- CSF specific transferrin
- Tau Protein
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Fluid, aural or nasal | Sterile container | Refrigerate ASAP | Send to Cleveland Clinic Laboratories on the day of collection |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Fluid |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 4 hours |
| Refrigerated | 72 hours |
| Frozen | Unacceptable |
Days Performed
Sun - Sat
Turnaround Time
2 - 5 days
Methodology
| Name | Description |
|---|---|
| Qualitative Immunofixation Electrophoresis |
Reference Range
Clinical Info
Detection of a beta-2 transferrin band by IFE is diagnostic for the presence of cerebrospinal fluid (CSF). This test is useful in the differential diagnosis for CSF otorrhea or CSF rhinorrhea. Beta-2 transferrin is not detected by this methodology in normal serum, tears, saliva, sputum, nasal, or aural fluid. NOTE: The beta-2 transferrin protein assay by IFE methodology is not a reliable method for detecting human perilymph due to the low sensitivity of the assay.