Bile Acids, Total | Cleveland Clinic Laboratories

Bile Acids, Total Print

Test Mnemonic

BILETO

CPT Codes

82239 - QTY (1)

Aliases

Biliary Acids, Total

Performing Laboratory

Cleveland Clinic Laboratories

Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
1 mL	Serum	SST (Gold)		Refrigerated	Allow specimen to clot completely at room temperature. Centrifuge within 2 hours of collection and refrigerate.

Alternate Specimen Requirements

Volume	Type	Container	Transport Temperature	Special Instructions
1 mL	Serum	Red Plain	Refrigerated	Allow specimen to clot completely at room temperature. Centrifuge and transfer the serum to a plastic CCL tube within 2 hours of collection and refrigerate.
1 mL	Plasma	Lithium heparin (Green)	Refrigerated	Centrifuge and transfer the plasma to a plastic CCL tube within 2 hours of collection and refrigerate.
1 mL	Plasma	Lithium heparin PST (Lt. Green)	Refrigerated	Centrifuge within 2 hours of collection and refrigerate.
1 mL	Plasma	EDTA (Lavender)	Refrigerated	Centrifuge and transfer the plasma to a plastic CCL tube within 2 hours of collection and refrigerate.

Minimum Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
0.5 mL

Stability

Environmental Condition	Description
Ambient	48 hours
Refrigerated	30 days
Frozen	30 days

Days Performed

Mon - Sat

Turnaround Time

1 - 3 days

Methodology

Name	Description
Enzymatic

Reference Range

Bile Acids, Total
Sex	Age From	Age To	Type	Range	Range Unit
	Days	5 Months	Normal	None established
	6 Months	23 Months	Normal	< 25.8	umol/L
	2 Years	4 Years	Normal	< 20.9	umol/L
	5 Years	9 Years	Normal	< 12.4	umol/L
	10 Years	19 Years	Normal	< 13.6	umol/L
	20 Years	59 Years	Normal	< 7.5	umol/L
	60 Years	999 Years	Normal	< 8.3	umol/L
				Pregnancy Reference Intervals (Non-fasting): First Trimester (up to 13 weeks gestation): < 15.3 umol/L
				Pregnancy Reference Interval (Non-fasting): Second Trimester (13 - 27 weeks gestation): < 11.4 umol/L
				Pregnancy Reference Interval (Non-fasting): Third Trimester (> 27 weeks gestation): < 10.4 umol/L

Special Info

The reference intervals for adults >20 years old were obtained using fasting blood specimens. Reference intervals for children, adults <20 years old and pregnant women were obtained using random blood draw specimens.

Clinical Info

Use for the in vitro quantitative determination of total bile acids in serum or plasma.

Clinical Limitation

Total bile acid concentration in serum is increased after meals; hence, samples should be collected under fasting conditions. This does not apply to women for whom intrahepatic cholestasis of pregnancy as a diagnostic consideration; these patients will need peak bile acid testing, and samples should be postprandial. This serum bile acid assay should not be used for patients receiving ursodeoxycholic acid, nor should it be used as the primary assay for the screening or diagnosis of genetic disorders of bile acid synthesis.