Specimen Requirements

Alternate Specimen Requirements

Stability

Days Performed

Sun - Sat

Turnaround Time

4 hours

Methodology

Reference Range

Special Info

Those specimens with a positive antibody screen will have antibody identification performed and will incur additional fees. Antibody may be too weak to be detected and/or identified. Antibody Titer will be done if indicated. All blood bank samples must be labeled with the patient’s full name, date of birth, medical record number (or other unique number), date and time of sample collection, and the employee ID of the phlebotomist. Please see internal operating procedures for specimens collected outside of the Cleveland Clinic health system.

Clinical Info

Identification of risk of hemolytic disease of the newborn. If the antibody screen is positive and the antibody has been associated with hemolytic disease of the fetus and newborn, it will reflex to do the antibody titration. The direct antiglobulin test detects in vivo sensitization of red cells with IgG or complement. Indications include transfusion reaction, hemolytic disease of the fetus and newborn, passenger lymphocyte syndrome following stem cell or solid organ transplantation, and immune hemolytic anemia. If IgG sensitization is detected, depending on the clinical situation, eluate testing for new red cell alloantibodies may be required.